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06-May-2016 16:04

The deleted chromosome 5 is paternal in origin in about 80% of de novo cases.

Loss of a small region in band 5p15.2 (cri du chat critical region) correlates with all the clinical features of the syndrome with the exception of the catlike cry, which maps to band 5p15.3 (catlike critical region).

The results suggest that 2 noncontiguous critical regions contain genes involved in this condition's etiology.

Affected females reach puberty, develop secondary sex characteristics, and menstruate at the usual time.The genital tract is usually normal in females except for a report of a bicornuate uterus.In males, testes are often small, but spermatogenesis is thought to be normal.Welcome to Delhi Sex Chat, the best SEX CHAT in India.

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These individuals may have more severe disease than those with isolated monosomy of 5p.



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